Sfp1, an unusual zinc finger protein, was previously identified as a gene that, when
overexpressed, imparted a nuclear localization defect. sfp1 cells have a reduced size and a …

Supercapacitors are engaged in the search for efficient electrode materials to convene
hybrid vehicles' utility requirements and renewable energy sources. State-of-art …

Quantifying the effect of vital resources on transcription (TX) and translation (TL) helps to
understand the degree to which the concentration of each resource must be regulated for …

Current biological models of epigenetic switches built on chromatin modifications lead to
strong constraints on the repertoire of dynamic behaviors for the system. We use the …

Background The analysis of gene expression using DNA microarrays provides genome
wide profiles of the genes controlled by the presence or absence of a specific transcription …

Background DNA sequence binding motifs for several important transcription factors happen
to be self-overlapping. Many of the current regulatory site identification methods do not …

In addition to gene network switches, local epigenetic modifications to DNA and histones
play an important role in all-or-none cellular decision-making. Here, we study the dynamical …

Background Characterizing transcription factor binding motifs is a common bioinformatics
task. For transcription factors with variable binding sites, we need to get many suboptimal …

One of the central reactions of homologous recombination is the invasion of a single strand
of DNA into a homologous duplex to form a joint molecule. Here we describe the isolation of …

Objectives High rates of depression and suicide and a lack of trained psychiatrists have
emerged as significant concerns in the low-income and middle-income countries (LMICs) …