[HTML][HTML] HIV infection and COVID-19 death: a population-based cohort analysis of UK primary care data and linked national death registrations within the …

K Bhaskaran, CT Rentsch, B MacKenna, A Schultze… - The lancet HIV, 2021 - thelancet.com
Background Whether HIV infection is associated with risk of death due to COVID-19 is
unclear. We aimed to investigate this association in a large-scale population-based study in …

[HTML][HTML] Case fatality risk of the SARS-CoV-2 variant of concern B. 1.1. 7 in England, 16 November to 5 February

DJ Grint, K Wing, E Williamson, HI McDonald… - …, 2021 - eurosurveillance.org
The SARS-CoV-2 B. 1.1. 7 variant of concern (VOC) is increasing in prevalence across
Europe. Accurate estimation of disease severity associated with this VOC is critical for …

[HTML][HTML] Factors associated with deaths due to COVID-19 versus other causes: population-based cohort analysis of UK primary care data and linked national death …

K Bhaskaran, S Bacon, SJW Evans… - The Lancet Regional …, 2021 - thelancet.com
Background Mortality from COVID-19 shows a strong relationship with age and pre-existing
medical conditions, as does mortality from other causes. We aimed to investigate how …

Risks of covid-19 hospital admission and death for people with learning disability: population based cohort study using the OpenSAFELY platform

EJ Williamson, HI McDonald, K Bhaskaran, AJ Walker… - bmj, 2021 - bmj.com
Objective To assess the association between learning disability and risk of hospital
admission and death from covid-19 in England among adults and children. Design …

Severity of severe acute respiratory system coronavirus 2 (SARS-CoV-2) alpha variant (B. 1.1. 7) in England

DJ Grint, K Wing, C Houlihan, HP Gibbs… - Clinical Infectious …, 2022 - academic.oup.com
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) alpha
variant (B. 1.1. 7) is associated with higher transmissibility than wild-type virus, becoming the …

[HTML][HTML] Changes in COVID-19-related mortality across key demographic and clinical subgroups in England from 2020 to 2022: a retrospective cohort study using the …

L Nab, EPK Parker, CD Andrews, WJ Hulme… - The Lancet public …, 2023 - thelancet.com
Background COVID-19 has been shown to differently affect various demographic and
clinical population subgroups. We aimed to describe trends in absolute and relative COVID …

Comparative effectiveness of sotrovimab and molnupiravir for prevention of severe covid-19 outcomes in patients in the community: observational cohort study with the …

B Zheng, ACA Green, J Tazare, HJ Curtis, L Fisher… - bmj, 2022 - bmj.com
Objective To compare the effectiveness of sotrovimab (a neutralising monoclonal antibody)
with molnupiravir (an antiviral) in preventing severe outcomes of covid-19 in adult patients …

[HTML][HTML] Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and …

K Bhaskaran, CT Rentsch, G Hickman, WJ Hulme… - PLoS …, 2022 - journals.plos.org
Background There is concern about medium to long-term adverse outcomes following acute
Coronavirus Disease 2019 (COVID-19), but little relevant evidence exists. We aimed to …

Waning effectiveness of BNT162b2 and ChAdOx1 covid-19 vaccines over six months since second dose: OpenSAFELY cohort study using linked electronic health …

EMF Horne, WJ Hulme, RH Keogh, TM Palmer… - bmj, 2022 - bmj.com
Objective To estimate waning of covid-19 vaccine effectiveness over six months after second
dose. Design Cohort study, approved by NHS England. Setting Linked primary care …

[HTML][HTML] OpenSAFELY: Representativeness of electronic health record platform OpenSAFELY-TPP data compared to the population of England

C Andrews, A Schultze, H Curtis, W Hulme… - Wellcome Open …, 2022 - ncbi.nlm.nih.gov
Background: Since its inception in March 2020, data from the OpenSAFELY-TPP electronic
health record platform has been used for more than 20 studies relating to the global COVID …