Sleep disordered breathing with excessive daytime sleepiness is a risk factor for mortality in older adults

NS Gooneratne, KC Richards, M Joffe, RW Lam… - Sleep, 2011 - academic.oup.com
Abstract Study Objectives: Excessive daytime sleepiness (EDS) is associated with increased
mortality in older adults, yet sleep disordered breathing (SDB), a common cause of …

Asthma patients who stop asthma biologics have a similar risk of asthma exacerbations as those who continue asthma biologics

MM Jeffery, JW Inselman, JT Maddux, RW Lam… - The Journal of Allergy …, 2021 - Elsevier
Background There is limited information about outcomes associated with stopping asthma
biologics. Objective To compare outcomes in people who stopped or continued asthma …

Validating parameters of a luciferase reporter gene assay to measure neutralizing antibodies to IFNβ in multiple sclerosis patients

R Lam, R Farrell, T Aziz, E Gibbs, G Giovannoni… - Journal of …, 2008 - Elsevier
Neutralizing antibodies (NAbs) occur in some of the multiple sclerosis (MS) patients
receiving interferon β (IFNβ) therapy. NAbs reduce drug bioavailabity and high NAb titers …

Adherence to asthma biologics: implications for patient selection, step therapy, and outcomes

JT Maddux, JW Inselman, MM Jeffery, RW Lam… - Chest, 2021 - Elsevier
Background Little is known about adherence to asthma biologics. Research Question Is
adherence to inhaled corticosteroid (ICS) associated with subsequent asthma biologic …

Breast cancer survivors willingness to participate in an acupuncture clinical trial: a qualitative study

MM Schapira, ER Mackenzie, R Lam, D Casarett… - Supportive Care in …, 2014 - Springer
Purpose Acupuncture is a complementary and alternative medicine (CAM) modality that
shows promise as a component of supportive breast cancer care. Lack of robust recruitment …

Best practices in implementing inpatient pediatric asthma pathways: a qualitative study

SV Kaiser, R Lam, MD Cabana, A Bekmezian… - Journal of …, 2020 - Taylor & Francis
Objective: Clinical pathways (operational versions of practice guidelines) can improve
guideline adherence and quality of care for children hospitalized with asthma. However …

Single-locus enrichment without amplification for sequencing and direct detection of epigenetic modifications

TT Pham, J Yin, JS Eid, E Adams, R Lam… - Molecular Genetics and …, 2016 - Springer
A gene-level targeted enrichment method for direct detection of epigenetic modifications is
described. The approach is demonstrated on the CGG-repeat region of the FMR1 gene, for …

[HTML][HTML] National decline in asthma exacerbations in United States during coronavirus disease 2019 pandemic

RW Lam, JW Inselman, MM Jeffery… - Annals of Allergy …, 2021 - ncbi.nlm.nih.gov
We present a unique case of a patient with no prominent GI symptoms before OIT, who
developed daily vomiting for 10 days after 3 weeks of starting OIT and had macro and …

A prediction model for asthma exacerbations after stopping asthma biologics

JW Inselman, MM Jeffery, JT Maddux, RW Lam… - Annals of Allergy …, 2023 - Elsevier
Background Little is known regarding the prediction of the risks of asthma exacerbation after
stopping asthma biologics. Objective To develop and validate a predictive model for the risk …

Asthma biologic trial eligibility and real-world outcomes in the United States

RW Lam, JW Inselman, MM Jeffery, JT Maddux… - Journal of …, 2022 - Taylor & Francis
Objective To compare the outcomes of real-world patients who would have been eligible for
asthma biologics to those who would not have been eligible. Methods We used data from …