QT interval prolongation and the risk of torsades de pointes: essentials for clinicians

KE Trinkley, R Lee Page, H Lien… - … medical research and …, 2013 - Taylor & Francis
Objective: QT interval prolongation signifies an increased risk of the life-threatening
arrhythmia torsades de pointes (TdP). The purpose of this paper is to review the diverse …

Phentermine/topiramate for the treatment of obesity

SM Smith, M Meyer, KE Trinkley - Annals of …, 2013 - journals.sagepub.com
OBJECTIVE To review the pharmacology, efficacy, and safety of phentermine/topiramate
(PHEN/TPM) in the management of obese patients. DATA SOURCES MEDLINE (1966-July …

Medication management of irritable bowel syndrome

KE Trinkley, MC Nahata - Digestion, 2014 - karger.com
Background: Irritable bowel syndrome (IBS) is a complex syndrome that is difficult to
manage. Here we present the evidence supporting medication treatments for specific IBS …

An electronically delivered patient-activation tool for intensification of medications for chronic heart failure with reduced ejection fraction: the EPIC-HF trial

LA Allen, G Venechuk, CK McIlvennan, RL Page… - Circulation, 2021 - Am Heart Assoc
Background: Major gaps exist in the routine initiation and dose up-titration of guideline-
directed medical therapies (GDMT) for patients with heart failure with reduced ejection …

Clinical implementation of pharmacogenomics via a health system-wide research biobank: the University of Colorado experience

CL Aquilante, DP Kao, KE Trinkley, CT Lin… - …, 2020 - Future Medicine
In recent years, the genomics community has witnessed the growth of large research
biobanks, which collect DNA samples for research purposes. Depending on how and where …

[HTML][HTML] Integrating the practical robust implementation and sustainability model with best practices in clinical decision support design: implementation science …

KE Trinkley, MG Kahn, TD Bennett, RE Glasgow… - Journal of Medical …, 2020 - jmir.org
Background Clinical decision support (CDS) design best practices are intended to provide a
narrative representation of factors that influence the success of CDS tools. However, they …

[HTML][HTML] Ontologizing health systems data at scale: making translational discovery a reality

TJ Callahan, AL Stefanski, JM Wyrwa, C Zeng… - NPJ Digital …, 2023 - nature.com
Common data models solve many challenges of standardizing electronic health record
(EHR) data but are unable to semantically integrate all of the resources needed for deep …

How dissemination and implementation science can contribute to the advancement of learning health systems

KE Trinkley, PM Ho, RE Glasgow… - Academic …, 2022 - journals.lww.com
Many health systems are working to become learning health systems (LHSs), which aim to
improve the value of health care by rapidly, continuously generating evidence to apply to …

[HTML][HTML] Clinician preferences for computerised clinical decision support for medications in primary care: a focus group study

KE Trinkley, WW Blakeslee, DD Matlock… - BMJ health & care …, 2019 - ncbi.nlm.nih.gov
Background To improve user-centred design efforts and efficiency; there is a need to
disseminate information on modern day clinician preferences for technologies such as …

Clinical pharmacists in primary care: provider satisfaction and perceived impact on quality of care provided

H Truong, ME Kroehl, C Lewis… - Sage Open …, 2017 - journals.sagepub.com
Purpose: The purpose of this study is to evaluate primary care provider satisfaction and
perceived impact of clinical pharmacy services on the disease state management in primary …