The complete set of prompts administered at random to participants
| Prompt | |
| 1 | Find two primary research articles demonstrating that Black Americans and predominantly Black communities have suffered from higher incidences of SARS-CoV-2 than White Americans and predominantly White communities. One of these articles should present the data as a rate of infection, while the other should present evidence of this statement as an OR. |
| 2 | Find an article in which <3% of healthcare workers without symptoms of COVID-19 tested positive for SARS-CoV-2 through antibody testing. Find another article in which more than 18% of asymptomatic healthcare workers tested positive for SARS-CoV-2 through antibody testing. |
| 3 | Find two articles in which the amount of C reactive protein measured in critically severe COVID-19 patients was at least 1.5 times greater than that of severe COVID-19 patients. |
| 4 | Find one article showing that essential workers, people receiving treatment for PTSD, and young adults are among groups with the greatest risk of developing suicidal thoughts as a result of the pandemic. Report their risk in terms of ORs. |
| 5 | Reports of the percentage of newborns born to COVID-19 positive mothers who demonstrate fever symptoms are variable across the literature. Find one article in which none of the newborns had a fever and find another article in which more than 20% of the newborns had a fever. These articles cannot be case reports of only a single patient. |
| 6 | Several articles have published descriptions of new-onset psychotic disorder-like symptoms in patients with COVID-19 (meaning they had no prior history of these symptoms). Find an article that reports on the success of treatment for psychotic-like symptoms in patients with COVID-19. Your answer should include the percentage of patients for whom these symptoms were resolved. |
| 7 | Find an article that describes a new-onset of demyelinating lesions in the central nervous systems of patients with severe or critical COVID-19. The article you select must have a study population of at least 20 patients with COVID-19 positive. |
| 8 | Peak infectiousness typically occurs around 2 days before symptom onset. Find an article with a sample size of at least 1000 confirmed COVID-19 cases that describe this information and also describes the number of transmission events attributable to pre-symptomatic individuals. |
| 9 | Find one article that reports a range of recorded COVID-19 incubation periods with a maximum value of more than 18 days. |
| 10 | Find one article that reports the presence of SARS-CoV-2 in the sweat of symptomatic patients with COVID-19. The study should have a sample size of at least 25 individuals. Report the number of patients with COVID-19 with positive sweat samples. |
| 11 | Individuals with recent or lifetime substance abuse disorder (SUD) diagnoses are at higher risk of requiring hospitalisation and ventilation treatments after contracting COVID-19. They are also at a greater risk of dying due to the disease. Find an article that supports these three points using data presented as ORs. Note: these data should reflect increased risk as a result of SUD independently of any other comorbid conditions. |
| 12 | Find an article that describes a 70% or greater decrease in regional ICU admissions as a result of enacting physical distancing measures. |
| 13 | During the COVID-19 pandemic, a greater proportion of obese individuals have reported having a difficult time eating healthfully or are eating less healthy foods compared with the general population. Find two articles that support this statement. One article should report the proportion of obese individuals eating less healthfully and the other should report on the same measure in the general population. |
| 14 | Chest CT scans of hospitalised patients with COVID-19 show predominantly bilateral pulmonary lesions as opposed to only unilateral involvement. This trend is even more pronounced in patients admitted to the ICU. Find an article whose findings support this statement. Report the incidence of bilateral and unilateral pulmonary lesions in these two patient groups (hospitalised patients and patients admitted to the ICU). |
| 15 | There is evidence that SARS-CoV-2 can cross the blood-brain barrier to invade the brain. Find an article that reports on histochemical analysis of post-mortem brain tissue from patients with COVID-19 in which more than 95% of the samples studied showed evidence of astrogliosis (variably or in all brain regions). |
| 16 | The COVID-19 pandemic has had pronounced effects on mental health and substance abuse rates. Find an article in which 28% or more of the general population reported increased alcohol intake. These findings must also show a positive correlation with a history of mental illness. |
| 17 | Find two articles providing evidence that transmission of SARS-CoV-2 from mother to baby can occur through the placenta. One of these articles should provide evidence of transmission through immunostaining techniques, while the other should provide evidence using transmission electron microscopy. |
| 18 | Find an article showing that study participants who received the Moderna vaccine had a 0% incidence of severe COVID-19 infection post-vaccination. |
ICU, intensive care unit; PTSD, post traumatic stress disorder.