Table 1

List of covariates, the output variable and demographic information for each cohort. Continuous variables are stated as mean (IQR), otherwise are the number of occurrences. only a subset of these variables (selected by recursive feature elimination procedure) enters in the final models.

MIMIC-III
(n=4314)
eICU-CRD
(n=10 306)
Demographics
Age at admission (years)83.5 (56–81)76.7 (56–79)
Gender (n)
 Male24915927
 Female18234379
Output variable (transfusion)
Transfused patients (n, % wrt total number of patients)2077 (48.15%)2712 (26.31%)
Covariates
Heart rate (bpm)92.9 (79.0–105.7)94.0 (79.9–106.5)
Mean blood pressure (mm Hg)78.9 (68.5–87.8)78.4 (67.6–87.5)
Systolic blood pressure (mm Hg)114.5 (99.0–129.0)108.1 (93–121)
Diastolic blood pressure (mm Hg)60.3 (54.7–65.2)62.6 (56.0–68.2)
Respiratory rate (breaths/min)21.2 (18.0–24.0)21.9 (17.8–24.4)
Haematocrit (%)28.4 (23.8–32.6)26.5 (20.7–31.6)
Haemoglobin (g/L)97 (80–112)87 (67–104)
White blood cell (×109/L)11.8 (7.2–14.1)11.7 (7.4–14.4)
Platelet (×109/L)227.5 (137.0–286.0)207 (129.0–263.0)
Creatinine (mg/dL)1.79 (0.85–1.88)1.73 (0.80–1.90)
Blood urea nitrogen (mg/dL)39.5 (19.0–51.0)39.2 (19.0–51.0)
Potassium (mEq/L)4.34 (3.80–4.70)4.38 (3.80–4.80)
Bicarbonate (mEq/L)22.6 (20.0–26.0)22.7 (20.0–26.0)
Amount blood transfused (mL)601.0 (375.0–750.0)571.9 (324.0–700.0)
Glucose (mg/dL)160.2 (106.0–174.0)153.2 (105.0–176.0)
Albumin (g/dL)3.17 (3.2–3.2)2.96 (2.8–3.1)
Temperature (°C)36.3 (36.0–36.7)36.4 (36.4–36.5)
Partial thromboplastin time (s)37.3 (26.1–37.9)35.3 (26.0–37.0)
  • eICU-CRD, eICU Collaborative Research Database; ICU, intensive care unit; MIMIC-III, Medical Information Mart for Intensive Care-III.