PT  - JOURNAL ARTICLE
AU  - Davy van de Sande
AU  - Michel E Van Genderen
AU  - Jim M. Smit
AU  - Joost Huiskens
AU  - Jacob J. Visser
AU  - Robert E. R. Veen
AU  - Edwin van Unen
AU  - Oliver Hilgers BA
AU  - Diederik Gommers
AU  - Jasper van Bommel
TI  - Developing, implementing and governing artificial intelligence in medicine: a step-by-step approach to prevent an artificial intelligence winter
AID  - 10.1136/bmjhci-2021-100495
DP  - 2022 Feb 01
TA  - BMJ Health & Care Informatics
PG  - e100495
VI  - 29
IP  - 1
4099  - http://informatics.bmj.com/content/29/1/e100495.short
4100  - http://informatics.bmj.com/content/29/1/e100495.full
SO  - BMJ Health Care Inform2022 Feb 01; 29
AB  - Objective Although the role of artificial intelligence (AI) in medicine is increasingly studied, most patients do not benefit because the majority of AI models remain in the testing and prototyping environment. The development and implementation trajectory of clinical AI models are complex and a structured overview is missing. We therefore propose a step-by-step overview to enhance clinicians’ understanding and to promote quality of medical AI research.Methods We summarised key elements (such as current guidelines, challenges, regulatory documents and good practices) that are needed to develop and safely implement AI in medicine.Conclusion This overview complements other frameworks in a way that it is accessible to stakeholders without prior AI knowledge and as such provides a step-by-step approach incorporating all the key elements and current guidelines that are essential for implementation, and can thereby help to move AI from bytes to bedside.Data sharing is not applicable as no datasets were generated and/or analysed for this study. Not applicable.